TCGA / GDC
Cancer genomics, transcriptomics, biospecimen, and clinical data.
Visit ResourceResearch
Bioinformatics and Cancer Genomics
Research focuses on bioinformatics and cancer genomics, spanning pan-cancer transcriptomic analysis, RNA alterations, single-cell variant detection, and accessible biomedical data resources.
01
Research Area
Cancer Genomics and Pan-Cancer Analysis
This work integrates genomic, transcriptomic, clinical, and other molecular data to study RNA alterations, tumor microenvironment composition, regulatory networks, and treatment response across cancer types.
Research Topics
Related Platforms and Publications
Data Resources
GTEx
Gene expression and genetic regulation across normal human tissues.
Visit ResourcePCAWG Legacy Data
Guidance for accessing legacy ICGC/PCAWG data after retirement of the former portal.
Visit ResourcePCAWG Xena Hub
Interactive exploration and visualization of PCAWG datasets.
Visit Resource
02
Research Area
Single-Cell Transcriptomics and Variant Detection
This work benchmarks computational methods for detecting single-nucleotide variants in single-cell RNA-sequencing data and evaluates how sequencing depth, gene expression, allele frequency, and genomic context influence performance.
Research Keywords
Representative Publication
Systematic comparative analysis of single-nucleotide variant detection methods from single-cell RNA sequencing data
Co-first author; study design and data analysis
03
Research Area
Bioinformatics Tools and Data Resources
Selected web tools and data resources associated with published work in cancer transcriptomics, cell-type analysis, and lncRNA annotation.
Resource
GEPIA3
An advanced pan-cancer analysis platform integrating gene expression, drug sensitivity, gene/protein interaction networks, regulatory relationships, and RNA alterations.
Corresponding author; project co-design and supervision
Resource
GEPIA2021
A web resource for cell type-level analysis of TCGA and GTEx bulk transcriptomic data using multiple deconvolution methods.
Corresponding author; study supervision
The GEPIA2021 server has shown intermittent availability; the publication link remains accessible.
Resource
AnnoLnc2
The current successor to AnnoLnc, providing systematic annotation of novel human and mouse lncRNAs.
Co-author of original AnnoLnc; pilot website testing
Fenglin Liu contributed to the original AnnoLnc pilot build and is listed in the previous AnnoLnc development team, not the AnnoLnc2 development team.